Plumb, G ; S. Olsen & G. Pappas (editors)
Title Brucellosis : Recent Developments in Diagnosis and Epidemiology Towards 'One Health'
9290449195 / 9789290449195
Inventory number 979573
2013. 30cm. Pp.295. Softbound.
'Brucellosis : Recent Developments in Diagnosis and Epidemiology' presents a comprehensive overview of the state of knowledge of the ecology of brucellosis, a clearer understanding of the current situation and a summary of the outlook for the future, so as to allow the disease to be neglected no longer, or at least to be recognised as neglected.
The study of zoonotic brucellosis served as a basis for some of the great early advances in epidemiology, yet the disease remains the most common chronic bacterial infection in the world. It continues to cause important medical, veterinary, socioeconomic and conservation problems, mainly because its overall burden remains underestimated and often neglected.
Brucellosis manifests anywhere and knows no borders, moving liberally amongst humans, livestock, and terrestrial and aquatic wildlife. There is a need, therefore, for critical deliberation of its epidemiology, pathogenesis, diagnosis, and prevention and management.
In responding to this need, the global scientific and technical community has recently made several advances : it has increased our understanding of molecular determinants and cell internalisation mechanisms; improved molecular characterisation techniques (leading to a better understanding of evolution, host specificity, and pathogenicity); developed more accurate multivariate empirical models of disease transmission and persistence probabilities; made progress in the integration of spatial epidemiology techniques; designed and implemented long-term adaptive risk management systems; developed new approaches to applying ecological principles to wildlife brucellosis in large landscape-scale environments; made innovative advances in vaccinology; and gained insights into emergent strains and novel hosts. Yet, despite these notable advances, there remain important challenges in the areas of risk assessment and management, the adoption of sustainable control interventions, and capacity building for improved epidemiological and economic decision-making.
In line with the emergence of the information age, exciting advances in brucellosis are being witnessed through the increasing global integration of brucellosis science and management communities. Indeed, one of the purposes of this issue of the OIE Scientific and Technical Review is to further encourage enterprising outreach amongst the human, wildlife, and livestock brucellosis communities, and thus deliberately nurture this continuing integration towards a One Health approach involving disease prevention and control programmes at the animal source.
As H.V. Wyatt observed, ‘History may repeat as farce, but diseases recur with historical memories.’
•Lessons from the history of brucellosis
•Brucellosis in terrestrial wildlife
•Epidemiology of brucellosis in domestic animals caused by Brucella melitensis, Brucella suis and Brucella abortus
•Persistence of brucellosis in pastoral systems
•Risks of Brucella abortus spillover in the Greater Yellowstone Area
•An ecological perspective on Brucella abortus in the western United States
•Wildlife reservoirs of brucellosis: Brucella in aquatic environments
•Pathogenesis and pathobiology of brucellosis in livestock